Standard Treatment  Neither radiation nor surgery can cure women with distant metastases, but both are used for local relief of symptoms.
    A number of chemotherapy regimens that are effective in the treatment of metastatic cervical cancer are also used to treat metastatic vaginal cancers—cisplatin, carboplatin and the combinations of mitomycin-C + vincristine + bleomycin + cisplatin and cisplatin + ifosfamide + etoposide .

Five-Year Survival  Less than 10 percent 

Investigational 
• Various doses and combinations of chemotherapeutic drugs are being evaluated, including cisplatin, 
  carboplatin, ifosfamide, etoposide, mitomycin-C, 5-FU , vincristine, vinblastine , mitoxantrone , bleomycin
  and methotrexate .